Evidence
20+ years of development. Scientifically supported. Practically proven.

Ruma develops safety and verification technologies for real-world appplications - for processes in which trust alone is not sufficient, but security, clear identificaton, reliable verification and tammper resistance are required.

Continuous development

Marker technology

Digital verification

Ruma Digital-System (Pro)

2026 | Latest Study: A two-year follow-up on the acceptance and impact of digitized urine testing among drug addicts
Actually used.
DOI: 10.1055/a-2848-9994
From control to verified personal responsibility - a paradigm shift.
- Significantly improved adherence and verified personal responsibility
- Less psychological stress due to decentralized testing
- High acceptance through greater flexibility in everyday life
- Reduced manipulation attempt through unpredictable testing

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The follow-up data show: The system is not only digitally activated, but is actively used - and the increased laboratory analysis provides objective, tamper-resistant evidence.


2023 | Digital Monitoring of Adherence for the Treatment of Drug Abuse
Higher acceptance and time savings - particularly among younger male participants
DOI 10.1055/a-2078-0959
- Independent of location
- Personal responsibility
- Compatible with work


2023 | Matrix Effects of Urine Marker Substances in LC-MS/MS
Analysis of Drug of Abuse
Influence of matrix and laboratory method can be reliably controlled
DOI 10.1097/JTM.0000000000000454


2023 | Betäubungsmittelkonsum unter Bewährungs-und Führungsaufsicht - Eine Langzeituntersuchung zum risikogruppenspezifischen Rückfallgeschehen unter Abstinenzauflagen
Positive initial results and relevance for official structures..
DOI: 10.1055/a-2173-8063


2022 | Comparative LCMS/MS Drug Analysis of paired Urine, Oral Fluid and Capillary Blood Samples in Addiction Therapy Comparison with urine, saliva and capillary blood.
Reliable analyses show clearly that urine is the most valuable matrix.
DOI: 10.36648/2386-5180.22.10.416


2020 | An innovative telemedicine approach to substitution and drug control
Scientific and practical validation of the digital process chain.
Suchtmed 22 (4) 1 - 5 (2020)


2018 | Process Reliability and Psychological Stress in Urine Sample Collection for Drug Testing: A Pilot Study
Suchtmed 22 (4) 1 - 5 (2020)
DOI: 10.9734/JALSI/2018/44565


2017 | Urine-kinetics of Low Molecular Polyethylene Glycols Following an Oral Capsule Ingestion
DOI: 10.9734/JALSI/2017/38741


2016 | IThe Influence of Foods and Beverages on Polyethylene Glycol Marker Detection in Urine
DOI: 10.4172/2155-6105.1000376
➡ 2006 - Marker technology | 2010 - Acceptance & Application | 2015 - Sports Medicine

2012 | Analysis

2010 | Compliance, burden reduction and acceptability

2008/2009 | Manipulation and detection

2005-2007 | Scientific basis and initial studies

